Sorry to be so negative about Oprah, y'all. I don't care for her - haven't for a long time (no kidding, right?) and I flew off the handle in her general direction.
That said, yes, LJ, I would have preferred it if Gayle had said "We are straight and very close friends" instead of "We are not gay, we're just very close friends." I just think that in every situation, it's better to say what you are than what you are not. There are just negative connotations attached to denying something in my mind. People regularly say "I'm not a bigot" or "I'm not a racist" or "I'm not against mixed marriages." Saying these things clearly implies (and should) that people who are those things are lesser people than the speaker is trying to paint him or herself as being, right? So when I hear "I'm not gay," I can't help but think the person saying it is implying, whether that is his or her intention or not (and I'm sure it's almost always not) that it is undesirable to be gay. I don't think I'm reading too much negativity into it in seeing it that way - I think I'm just responding to the language and what it implies when it's used one way versus another.
Similarly, there are subtle differences in the way a straight woman might say about a gay man she finds attractive "what a waste." If a straight woman says, "What a loss for straight women everywhere" or "Our loss is gay men's gain" (or any derivation thereof that clearly implies that), then that's perfectly acceptable to me. Or if she says it like, "Damn - I was hoping to have a shot at him," that is, too. But when she's a co-worker, for example, who has clearly told you in the past that she would never date a guy she works with and then says to you one day, as one of mine did, "I hope the next guy that sits across from me isn't gay," that's implying something entirely different.
I swear I'm really not one of these sticklers for political correctness like I come off as being - I really do give people the benefit of the doubt when it comes to these kinds of things. But when such implications come up again and again from the same person, I start to think that if it looks like a bigot and quacks like a bigot, it probably is a bigot.