Pennsylvania has a "Mount CAR-mul." I understand there is a "New MAD-rid" in Missouri and a "KAY-ro" (Cairo) in Illinois (and is that Ill-i-noy, Ill-uh-noy, Ill-i-noise, or Ill-uh-noise?).
The worst news reader mispronunciation I ever heard wasn't of a place name. One December when I was in junior high, a reader for the local TV station pronounced the name of the Jewish Festival of Lights as "Cha-NOO-kuh." He was fired forthwith.