Gah! All of them!
Alma a lot. None of this was her fault. She wasn't a harridan or bitch from hell, she was the girl next door caught up in circumstances she couldn't control and had less understanding. She didn't get what she wanted (Ennis), but got what she needed (Monroe). Things will look up for her.
Alma Jr./Jenny, least pity of all. They're from broken homes, but all of their parents clearly love them, care for them, still see them constantly and take a sharp interest in them, so they're not bereft of much.
Lureen some pity. She chose the wrong man to go up against her daddy and despite having all of the material goods life can offer, including having children and a male child at that, she didn't have the love and attention from the one man she truly expected it from.
Cassie., little pity. She's just another victim in the dating game. You play you pay. Not all relationships work out, many many many women have loved men who didn't love them back and dropped them without any kind of explantion. Welcome to the party, pal.
Jack's Mom, great pity. Her life was hard and loveless and she sought love and comfort where she could in her desolate, isolated life - the church and in her son. After losing him, she had nothing to comfort her anymore other than her spirituality and in the end, probably die alone, since John Twist will probably pre-decease her.
John Twist, hmmm...what we hear is that those who abuse are merely continuing the cycle of abuse, so that means John Twist somewhere in his childhood had a brutal fatherand/or mother...but someone can choose not to be like their parents - as Ennis showed - so John Twist didn't have to be how he was, but he did nothing to change things, subjecting his son and probably his wife to casual abuse. No pity.
Jack and Ennis, Jack more than Ennis. Ennis, because his repression made him so shy and so introverted he was hardly alive. His father was probably an abusive horror and he was lucky to have lost his parents young, so that the poison of such upbringing didn't sink to the core of him, but he was still scarred by the Earl and Rich incident and always would be. He was terrified and remained forever in a prison of his own making, unable to reach for happiness and live to the fullest when the opportunity came for him.
A chance few of us get, so my sympathy for him is tempered by this.
Jack, because he suffered from his father, his upbringing, and finally suffering from the one person he might have expected better from. The man who loved him above all others. There was nothing that came to him the 'right way'. Yet, he remained upbeat and hopeful for decades, a dream sustaining him, until finally, a failed romantic, embittered at the end, he died.
Jack above all.