Cranium is really fun. Especially for four or more players. You have to do all sorts of stuff to advance around the board, like Pictionary-type drawings for your partner(s) to guess at, sculpting the answer out of clay for them to guess at, answering trivia questions, and doing a full-blown charade. The last time I played it with a bunch of people, I laughed so hard I hurt myself when Ed pantomimed a "Ticker-Tape Parade." You had to be there, but he kinda did the Jarhead-like fake trumpet blowing while throwing little bits of a ripped up paper all over the place and high-stepping. Well, it may be that it was funnier after a couple of adult beverages, too...
HuggerMugger is fun too. Similar to Cranium, but without the charades and pictionary stuff - you do spelling, word scrambles, trivia, and vocabulary to win.