Which Oprah thing?
Just that ongoing "feud" they had because she supposedly refused to appear on his show. That's been going for years. She finally did appear and it ended up not doing much to allay the feud thing. That's what that Super Bowl ad was about, where she and he are sitting on a couch, he's got his arm around her, and they're watching the game, she in a Bears jersey, he in a Colts one. He says something like, "Even though you're for the Bears and I'm for the Colts, we're in love, so everyone wins!" Still milkin' it after all these years.
I do think some of his Top Ten List stuff is funny, but we can only credit the writers for that - I don't know that he has much input into those.